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. 1995 Mar;38(4):835-6.
doi: 10.1016/0031-9422(94)00771-k.

Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

M Andersson  1 , O Bergendorff, M Nielsen, O Sterner, R Witt, J Ai, A Lu, A M Wang
Affiliations

Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

M Andersson et al. Phytochemistry. 1995 Mar.

Abstract

S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.

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