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. 1995 Mar;51(1):142-50.

Asymptotic confidence bands for generalized nonlinear regression models

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  • PMID: 7766770

Asymptotic confidence bands for generalized nonlinear regression models

C Cox et al. Biometrics. 1995 Mar.

Abstract

Asymptotic confidence bands for generalized nonlinear regression models are developed. These are based on a combination of the S method of Scheffe, together with the delta method which is used to approximate the mean function by a linear combination of the parameters. The approach can be used in any situation where large sample theory can be applied to yield asymptotically normal estimates of the parameters, together with a consistent estimate of the large sample covariance matrix. Alternative formulations for various special cases allow the use of restricted range bands. A number of examples are given, including a pharmacokinetic model, a logit model with a background response rate, and a parametric survival model.

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