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Clinical Trial
. 1994 Dec;33(12):824-6.

[Clinical research on the treatment of acute leukemia with autologous bone marrow transplantation]

[Article in Chinese]
H J Zheng  1 , Y Su, Y H Zhao
Affiliations
  • PMID: 7768141
Clinical Trial

[Clinical research on the treatment of acute leukemia with autologous bone marrow transplantation]

[Article in Chinese]
H J Zheng et al. Zhonghua Nei Ke Za Zhi. 1994 Dec.

Abstract

38 cases of acute leukemia were treated with autologous bone marrow transplantation (ABMT). The marrow was purged with hyperthermia of 42 degrees C in vitro for one hour in microwave. Twenty-two among them were AML (CR1). Sixteen were ALL (CR1). The mean age was 26 (10-43) years. All the patients were engrafted successfully after ABMT. Mean DFS was 21 (3-69) months. Four cases relapsed at 3 to 8 months after ABMT. Two patients with ALL developed central nervous system leukemia at 12 and 15 months respectively after ABMT. The DFS and probability of relapse at 5 years were 67.8% and 16.8% respectively for all patients.

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