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Case Reports
. 1995 Jan-Feb;13(1):103-6.

Thrombocytopenia responsive to warfarin in a patient with systemic sclerosis--systemic lupus erythematosus overlap

M Kuwana  1 , J Kaburaki, M Hirakata, T Tojo, M Handa, Y Ikeda
Affiliations
  • PMID: 7774087
Case Reports

Thrombocytopenia responsive to warfarin in a patient with systemic sclerosis--systemic lupus erythematosus overlap

M Kuwana et al. Clin Exp Rheumatol. 1995 Jan-Feb.

Abstract

We report a patient with overlapping systemic sclerosis-systemic lupus erythematosus who developed refractory thrombocytopenia and recurrent thromboses. Coagulation and platelet labeling studies revealed that platelets were being consumed by the thrombus formation, and anticoagulation with warfarin dramatically increased the platelet count. This case report suggests that platelet consumption due to thrombus formation is one of the causes of thrombocytopenia in patients with rheumatic disease.

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