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Review
. 1995 Jun 16;81(6):825-8.
doi: 10.1016/0092-8674(95)90000-4.

Qualifying for the license to replicate

T T Su  1 , P J Follette, P H O'Farrell
Affiliations
Review

Qualifying for the license to replicate

T T Su et al. Cell. .
No abstract available

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Figures

Figure 1
Figure 1. A Model for Limiting DNA Replication to Once per Cell Cycle
Formation of a functional replication origin (green) involves assembly of essential replication factors (blue spheres) onto DNA at a site marked by an origin recognition complex (ORC) (gray spheres). Origin firing (pink) involves the initiation of replication forks from assembled origins. Some replication factors travel with the fork, while others dissociate or remain at the origin, resulting in a spent origin. Assembly and firing of origins are confined to different parts of the cell cycle (green and pink, respectively), thereby limiting initiation of DNA replication to once per cell cycle.
See this image and copyright information in PMC

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