Combined therapeutic approach for extraorbital sebaceous carcinoma in a Torre's syndrome

Abstract

Extraocular sebaceous carcinomas are extremely uncommon neoplasms. More exceptional is their association with an internal malignancy as first described separately by Torre and Muir in 1967. We report the first use of combined adjuvant radio- and chemotherapy in a sebaceous carcinoma of the anal margin in a Torre's syndrome. An interesting partial response was attained before the patient died from general debility. The therapeutic approach is discussed.