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. 1995 Apr;39(4):1003-6.
doi: 10.1128/AAC.39.4.1003.

Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects

A Shah  1 , J Lettieri, D Nix, J Wilton, A H Heller
Affiliations

Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects

A Shah et al. Antimicrob Agents Chemother. 1995 Apr.

Abstract

The effects of age and gender on the pharmacokinetics of high-dose intravenous ciprofloxacin in a healthy volunteer study were investigated. Plasma ciprofloxacin concentrations were higher in the elderly than in the young, and the pharmacokinetic parameters were not significantly different between the genders. Ciprofloxacin was well tolerated, with the majority of adverse events related to local reactions at the IV site.

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References

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