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Clinical Trial
. 1976 May;15(2):112-5.
doi: 10.1093/rheumatology/15.2.112.

Sulindac in osteoarthrosis of the hip

P A Dieppe, H C Burry, R Grahame, T Perera
Clinical Trial

Sulindac in osteoarthrosis of the hip

P A Dieppe et al. Rheumatol Rehabil. 1976 May.

Abstract

Sulindac (400 mg/day) has been compared with ibuprofen (1200 mg/day) in 40 patients with osteoarthrosis of the hip, over an eight-week period, in a double-blind controlled clinical trial. The two drugs were comparable in terms of patient preference, effects on hip movements, and toxicity. Sulindac showed superior analgesic properties to ibuprofen, resulting in a significantly greater reduction in pain on weight-bearing and with passive movements (P less than 0.01).

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