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. 1995 Mar;39(3):771-4.
doi: 10.1128/AAC.39.3.771.

Identification of a carbenicillin-hydrolyzing beta-lactamase in Alcaligenes denitrificans subsp. xylosoxydans

D Decré  1 , G Arlet, E Bergogne-Bérézin, A Philippon
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Identification of a carbenicillin-hydrolyzing beta-lactamase in Alcaligenes denitrificans subsp. xylosoxydans

D Decré et al. Antimicrob Agents Chemother. 1995 Mar.

Abstract

Eleven strains of Alcaligenes denitrificans subsp. xylosoxydans produced a beta-lactamase with a pI of 5.7 with kinetic data characteristic of a PSE-1-type enzyme. A CARB-type enzyme was identified by using an intragenic DNA probe of blaCARB. Hybridization of genomic DNA after XbaI restriction and pulsed-field electrophoresis suggested a chromosomal location for the gene.

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