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Clinical Trial
. 1976 Jun;11(3):295-302.

L-tryptophan in depression

T Farkas, D L Dunner, R R Fieve
  • PMID: 779855
Clinical Trial

L-tryptophan in depression

T Farkas et al. Biol Psychiatry. 1976 Jun.

Abstract

L-tryptophan, the amino acid precursor of serotonin, was administered to 16 depressive patients in a double-blind study of its potential antidepressant efficacy. Antidepressant responses were observed in one of ten unipolar patients and in three of six bipolar patients. These results are discussed in the context of possible interactions of amines with electrolyte systems in the etiology of affective illness.

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