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Case Reports
. 1994 Aug 15;52(2):188-95.
doi: 10.1002/ajmg.1320520213.

Diamniotic placentation associated with omphalopagus conjoined twins: implications for a contemporary model of conjoined twinning

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Case Reports

Diamniotic placentation associated with omphalopagus conjoined twins: implications for a contemporary model of conjoined twinning

R P Kapur et al. Am J Med Genet. .

Abstract

We have studied omphalopagus conjoined twins with a diamniotic monochorionic placenta. Although conjoined twins usually present in a single amniotic sac, one other example of diamniotic placenta has been reported in omphalopagus twins [Weston et al., 1990: Am J Med Genet 37:558-561]. Most theories concerning the pathogenesis of conjoined twinning exclude the possibility of diamniotic placentation. However, Spencer [1992: Teratology 45:591-602] recently elaborated a model for conjoined twinning based on duplication of organizing centers (primitive streaks) during gastrulation. We have considered the fate of embryonic membranes according to this model of omphalopagus twinning and show that diamniotic placentation is a predictable outcome.

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