Depression of lymphocyte response to concanavalin A in rabbits infected with Treponema pallidum (Nichols strain)
- PMID: 780277
- PMCID: PMC420882
- DOI: 10.1128/iai.14.1.320-322.1976
Depression of lymphocyte response to concanavalin A in rabbits infected with Treponema pallidum (Nichols strain)
Abstract
Peripheral blood lymphocytes isolated from rabbits in the early stages of Treponema pallidum infection responded poorly when exposed to concanavalin A in vitro. Maximal depression of blastogenesis occurred when lymphocytes were cultured in the presence of autologous serum in comparison with fetal calf or normal homologous rabbit serum.
Similar articles
-
Cell-mediated immunity in Treponema pallidum infected rabbits: in vitro response of splenic and lymph node lymphocytes to mitogens and specific antigens.Clin Exp Immunol. 1980 Jan;39(1):38-43. Clin Exp Immunol. 1980. PMID: 6993066 Free PMC article.
-
Selective in vitro response of thymus-derived lymphocytes from Treponema pallidum-infected rabbits.Infect Immun. 1977 Dec;18(3):603-11. doi: 10.1128/iai.18.3.603-611.1977. Infect Immun. 1977. PMID: 338485 Free PMC article.
-
Modulation of normal lymphocyte stimulation by serum from Treponema pallidum-infected rabbits.Cell Immunol. 1980 Jul 15;53(1):29-38. doi: 10.1016/0008-8749(80)90423-2. Cell Immunol. 1980. PMID: 6996838 No abstract available.
-
Characterization of lymphocyte responsiveness in early experimental syphilis. I. In vitro response to mitogens and Treponema pallidum antigens.J Immunol. 1980 Jan;124(1):454-60. J Immunol. 1980. PMID: 6153102
-
Cell-mediated immunity during syphilis.Br J Vener Dis. 1978 Jun;54(3):144-50. doi: 10.1136/sti.54.3.144. Br J Vener Dis. 1978. PMID: 350348 Free PMC article. Review.
Cited by
-
Parasitism by virulent Treponema pallidum of host cell surfaces.Infect Immun. 1977 Jul;17(1):174-86. doi: 10.1128/iai.17.1.174-186.1977. Infect Immun. 1977. PMID: 328394 Free PMC article.
-
Lymphocyte function in experimental endemic syphilis of Syrian hamsters.Immunology. 1985 Sep;56(1):9-21. Immunology. 1985. PMID: 2931353 Free PMC article.
-
Host defense mechanisms in secondary syphilitic lesions: a role for IFN-gamma-/IL-17-producing CD8+ T cells?Am J Pathol. 2010 Nov;177(5):2421-32. doi: 10.2353/ajpath.2010.100277. Epub 2010 Oct 1. Am J Pathol. 2010. PMID: 20889558 Free PMC article.
-
Response of syphilitic rabbits to reinfection with homologous and heterologous Treponema pallidum strains.Infect Immun. 1984 Sep;45(3):561-5. doi: 10.1128/iai.45.3.561-565.1984. Infect Immun. 1984. PMID: 6381307 Free PMC article.
-
Reappraisal of lymphocyte responsiveness to concanavalin A during experimental syphilis: evidence that glycosaminoglycans in the sera and tissues interfere ith active binding sites on the lectin and not with the lymphocytes.Infect Immun. 1982 Feb;35(2):552-9. doi: 10.1128/iai.35.2.552-559.1982. Infect Immun. 1982. PMID: 7035366 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources