Comparative Study
doi: 10.1016/s0140-6736(78)91266-7.
Matching for HLA antigens of A, B, and DR loci in renal transplantation by Eurotransplant
- PMID: 78047
- DOI: 10.1016/s0140-6736(78)91266-7
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Comparative Study
Matching for HLA antigens of A, B, and DR loci in renal transplantation by Eurotransplant
Lancet.
.
Abstract
79 patients and their respective cadaveric kidney donors were typed for HLA-A, HLA-B, and HLA-DR antigens using frozen stored spleen lymphocytes and fresh peripheral-blood lymphocytes. The kidney-graft survival-rate at 3 to 18 months was highest when donor and recipient shared one or two DR antigens and three or four A and B antigens. The graft-survival rate was significantly higher (87 +/- 6%) at 18 months in these patients than in less well matched patients (48 +/- 9%).
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