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Comparative Study
. 1978 Jun 17;1(8077):1278-81.
doi: 10.1016/s0140-6736(78)91266-7.

Matching for HLA antigens of A, B, and DR loci in renal transplantation by Eurotransplant

G G Persijn, B W Gabb, A van Leeuwen, A Nagtegaal, J Hoogeboom, J J van Rood
Comparative Study

Matching for HLA antigens of A, B, and DR loci in renal transplantation by Eurotransplant

G G Persijn et al. Lancet. .

Abstract

79 patients and their respective cadaveric kidney donors were typed for HLA-A, HLA-B, and HLA-DR antigens using frozen stored spleen lymphocytes and fresh peripheral-blood lymphocytes. The kidney-graft survival-rate at 3 to 18 months was highest when donor and recipient shared one or two DR antigens and three or four A and B antigens. The graft-survival rate was significantly higher (87 +/- 6%) at 18 months in these patients than in less well matched patients (48 +/- 9%).

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