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Review
. 1994 Dec;127(6 Pt 2):1783-7.
doi: 10.1083/jcb.127.6.1783.

Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction

E M Rosen  1 , S K Nigam, I D Goldberg
Affiliations
Review

Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction

E M Rosen et al. J Cell Biol. 1994 Dec.

Abstract

Epithelia and mesenchyme interact during various physiologic and pathologic processes. Scatter factor is a mesenchyme-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. Recent studies suggest that scatter factor and its receptor (c-met) mediate mesenchyme/epithelia signalling and even interconversion. In this mini-review, we will discuss how scatter factor and c-met may mediate interactions between mesenchyme and epithelia during embryogenesis, organ repair, and neoplasia.

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References

    1. J Biol Chem. 1994 Feb 11;269(6):4152-60 - PubMed
    1. Biochem Biophys Res Commun. 1989 Sep 15;163(2):967-73 - PubMed
    1. Cancer Res. 1991 Oct 1;51(19):5315-21 - PubMed
    1. J Cell Biol. 1993 Apr;121(1):145-54 - PubMed
    1. Cancer Res. 1994 Apr 1;54(7):1630-3 - PubMed

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