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. 1994 Sep;38(9):2197-9.
doi: 10.1128/AAC.38.9.2197.

Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species

K Yazawa  1 , Y Mikami, T Sakamoto, Y Ueno, N Morisaki, S Iwasaki, K Furihata
Affiliations

Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species

K Yazawa et al. Antimicrob Agents Chemother. 1994 Sep.

Abstract

A survey of five Nocardia spp. with respect to susceptibility towards three macrolides (erythromycin, rokitamycin, and midecamycin) showed that the Nocardia spp. have different susceptibility profiles. Most of the resistance was due to the inactivation of the macrolides by phosphorylation, glycosylation, reduction, deacylation, or a combination thereof.

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