Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Dec 9;87(2):187-92.
doi: 10.1016/0304-3835(94)90221-6.

Status of antioxidant systems in human carcinoma of uterine cervix

N Balasubramaniyan  1 , S Subramanian, S Govindasamy
Affiliations

Status of antioxidant systems in human carcinoma of uterine cervix

N Balasubramaniyan et al. Cancer Lett. .

Abstract

Lipid peroxides, glutathione content and the activities of antioxidant enzymes were estimated in patients who had carcinoma of the uterine cervix, and the values were compared with those of normal. The results showed a remarkable reduction in glutathione content and in the activities of catalase and superoxide dismutase in neoplastic tissue in stages II, III and IV (P < 0.001) whereas the activities of glutathione peroxidase and glutathione reductase were significantly lower in stage III and IV patients than that of normal controls. The tissue level of lipid peroxides and the activity of glutathione-S-transferase were found to be significantly higher than that of normals from stage II onwards. These observations suggested the impaired antioxidant status in carcinoma of the uterine cervix.

PubMed Disclaimer