Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1994 Sep;32(9):2266-9.
doi: 10.1128/jcm.32.9.2266-2269.1994.

Comparison of plasma PCR and bronchoalveolar lavage fluid culture for detection of cytomegalovirus infection in adult bone marrow transplant recipients

M M Aspin  1 , G M Gallez-Hawkins, T D Giugni, B Tegtmeier, D J Lang, G M Schmidt, S J Forman, J A Zaia
Affiliations
Comparative Study

Comparison of plasma PCR and bronchoalveolar lavage fluid culture for detection of cytomegalovirus infection in adult bone marrow transplant recipients

M M Aspin et al. J Clin Microbiol. 1994 Sep.

Abstract

Plasma PCR for human cytomegalovirus (CMV) DNA was compared with bronchoalveolar lavage (BAL) fluid culture as an indicator for disseminated CMV infection. Thirteen (32.5%) of 40 consecutive bone marrow transplant (BMT) recipients were BAL fluid culture positive for CMV on day 35 post-BMT, and 9 (69%) of the 13 had positive plasma PCRs between days 28 and 49. Of the 27 with negative BAL fluid cultures, 2 (7%) had positive plasma PCRs (P < 0.001). Plasma CMV DNA in BMT recipients is a useful clinical marker for serious infection.

PubMed Disclaimer

References

    1. Rev Infect Dis. 1982 Nov-Dec;4(6):1119-32 - PubMed
    1. Transplantation. 1993 Aug;56(2):330-4 - PubMed
    1. J Clin Microbiol. 1985 Feb;21(2):217-21 - PubMed
    1. J Infect Dis. 1986 Mar;153(3):478-88 - PubMed
    1. N Engl J Med. 1988 Jan 14;318(2):70-5 - PubMed

Publication types

MeSH terms