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Clinical Trial
. 1994 Sep;9(3):139-43.
doi: 10.1097/00004850-199409000-00001.

A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia. The Venlafaxine French Inpatient Study Group

G E Clerc  1 , P Ruimy, J Verdeau-Pallès
Affiliations
Clinical Trial

A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia. The Venlafaxine French Inpatient Study Group

G E Clerc et al. Int Clin Psychopharmacol. 1994 Sep.

Abstract

The antidepressant efficacy and short-term safety of venlafaxine and fluoxetine were compared in 68 patients hospitalized with major depression and melancholia. Venlafaxine was superior in efficacy to fluoxetine; total scores for both the MADRS and the HAM-D were significantly (p < or = 0.05) lower in the venlafaxine group than in the fluoxetine group at Weeks 4 and 6. Overall tolerance was similar for the two treatments.

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