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. 1995 Feb;69(2):1306-9.
doi: 10.1128/JVI.69.2.1306-1309.1995.

Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

A A Scalzo  1 , S L Elliott, J Cox, J Gardner, D J Moss, A Suhrbier
Affiliations

Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720)

A A Scalzo et al. J Virol. 1995 Feb.

Abstract

The use of synthetic peptides representing cytotoxic T-cell (CTL) epitopes for human vaccination requires the identification of a suitable adjuvant formulation. A single immunization with Montanide ISA720/tetanus toxoid/YPHFMPTNL protected mice against murine cytomegalovirus and induced epitope-specific CTL. Such formulations will find application in peptide-based CTL anti-viral vaccines.

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