Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 May;3(5):1215-24.
doi: 10.1093/nar/3.5.1215.

Fluorescent 2'(3')-O-aminoacylnucleosides-acceptor substrates for ribosomal peptidyltransferase+

S Chládek, D Ringer, E M Abraham
Free PMC article

Fluorescent 2'(3')-O-aminoacylnucleosides-acceptor substrates for ribosomal peptidyltransferase+

S Chládek et al. Nucleic Acids Res. 1976 May.
Free PMC article

Abstract

2'(3')-O-L-Phenylalanylderivatives of fluorescent 1,N6-ethenoadenosine and 3,N4-ethenocytidine were prepared by chemical synthesis. Both compounds are good acceptor substrates in ribosomal peptidyltransferase reactions. Since these compounds cannot form Watson-Crick base pairs, the results indicate that the terminal aminoacyladenosine unit of AA-tRNA is bound to ribosomal protein on the acceptor site of peptidyltransferase and not to rRNA.

PubMed Disclaimer

References

    1. Nature. 1963 Mar 16;197:1076-7 - PubMed
    1. Biochem Biophys Res Commun. 1972 Jan 31;46(2):597-604 - PubMed
    1. Biochemistry. 1974 Jun 18;13(13):2727-35 - PubMed
    1. Eur J Biochem. 1974 Jun 15;45(2):425-9 - PubMed
    1. Biochemistry. 1973 Dec 4;12(25):5135-8 - PubMed

Publication types

LinkOut - more resources