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Case Reports
. 1994 Aug;72(8):616-8.
doi: 10.1007/BF00227455.

Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination

A Habior  1 , B Walewska-Zielecka, E Butruk
Affiliations
Case Reports

Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination

A Habior et al. Clin Investig. 1994 Aug.

Abstract

Two cases (first cases from Poland and Eastern Europe) with liver injury due to amoxycillin-clavulanic acid (augmentin) are reported. Pruritus and jaundice were the main symptoms. Liver biopsy revealed mixed hepatocellular-cholestatic liver injury in both cases. In addition, in one case the microgranulomalike aggregate of inflammatory cells was found. Clinical and laboratory abnormalities returned to normal within 13 weeks.

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