Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1995 Jan 16;358(1):1-3.
doi: 10.1016/0014-5793(94)01368-b.

Persistent oxidative stress in cancer

S Toyokuni  1 , K Okamoto, J Yodoi, H Hiai
Affiliations
Free article
Review

Persistent oxidative stress in cancer

S Toyokuni et al. FEBS Lett. .
Free article

Abstract

DNA of cancers such as renal cell carcinoma and mammary invasive ductal carcinoma, is persistently exposed to more oxidative stress than that of adjacent normal tissue. We suggest that the concept of 'persistent oxidative stress in cancer' may open up a new research area, explaining part of the characteristic tumor biology of cancer such as activated transcription factors and proto-oncogenes, genomic instability, chemotherapy-resistance, invasion and metastasis.

PubMed Disclaimer

Publication types

LinkOut - more resources