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. 1994;11(3):149-60.
doi: 10.1093/imammb/11.3.149.

A probabilistic model for detecting coding regions in DNA sequences

A Thomas  1 , M H Skolnick
Affiliations

A probabilistic model for detecting coding regions in DNA sequences

A Thomas et al. IMA J Math Appl Med Biol. 1994.

Abstract

A probabilistic model is presented to predict whether or not an anonymous sequence of DNA contains exons. The method is shown to be at least as reliable as Grail, a well-known neural network solution to the problem, and to be significantly more amenable to customization for specific prediction problems.

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