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Clinical Trial
. 1976 Jul-Aug;19(4):677-82.
doi: 10.1002/1529-0131(197607/08)19:4<677::aid-art1780190404>3.0.co;2-a.

Combination therapy with naproxen and aspirin in rheumatoid arthritis

R F Willkens, E J Segre
Clinical Trial

Combination therapy with naproxen and aspirin in rheumatoid arthritis

R F Willkens et al. Arthritis Rheum. 1976 Jul-Aug.

Abstract

Thirty-six patients with rheumatoid arthritis were studied to determine the effectiveness and safety of combined therapy with naproxen and aspirin. An 8-week double-blind crossover trial was performed in which naproxen and placebo were administered on a background of constant-dose aspirin. Combination therapy was demonstrated to be more effective than aspirin alone. Tolerance of the two regimens was comparable.

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