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. 1994 Oct;38(10):2495-7.
doi: 10.1128/AAC.38.10.2495.

Azole resistance in oropharyngeal Candida albicans strains isolated from patients infected with human immunodeficiency virus

X He  1 , R N Tiballi, L T Zarins, S F Bradley, J A Sangeorzan, C A Kauffman
Affiliations

Azole resistance in oropharyngeal Candida albicans strains isolated from patients infected with human immunodeficiency virus

X He et al. Antimicrob Agents Chemother. 1994 Oct.

Abstract

For 212 oropharyngeal isolates of Candida albicans, the fluconazole MICs for 50 and 90% of strains tested were 0.5 and 16 micrograms/ml, respectively, and those of itraconazole were 0.05 and 0.2 micrograms/ml, respectively. Of 16 isolates for which fluconazole MICs were > 64 micrograms/ml, itraconazole MICs for 14 were < or = 0.8 micrograms/ml and for 2 were > 6.4 micrograms/ml. Most fluconazole-resistant strains remained susceptible to itraconazole; whether itraconazole will prove effective for refractory thrush remains to be shown.

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