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Comparative Study
. 1995 Feb;171(2):447-50.
doi: 10.1093/infdis/171.2.447.

Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992

V A Arankalle  1 , S A Tsarev, M S Chadha, D W Alling, S U Emerson, K Banerjee, R H Purcell
Affiliations
Comparative Study

Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992

V A Arankalle et al. J Infect Dis. 1995 Feb.

Abstract

The age-specific seroprevalence of antibody to hepatitis A virus (HAV) and antibody to hepatitis E virus (HEV) were studied in persons in Pune, India, where both viruses are endemic. The data showed that HAV infected the majority of persons by age 3 years and virtually 100% by late childhood. In contrast, infection with HEV was rare in children and did not reach peak prevalence (33%-40%) until early adulthood. The reason for the differences in infection rates between HAV and HEV is not known. Age-specific antibody patterns in serum samples obtained 10 years apart show that neither HAV nor HEV has diminished in medical importance in this Indian community.

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