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. 1978 Apr;11(4):357-61.
doi: 10.1111/j.1399-0039.1978.tb01268.x.

Association of HLA antigen a9 with progressive systemic sclerosis (scleroderma)

P J Clements, G Opelz, P I Terasaki, M R Mickey, D Furst

Association of HLA antigen a9 with progressive systemic sclerosis (scleroderma)

P J Clements et al. Tissue Antigens. 1978 Apr.

Abstract

Upon evaluation of 40 subjects with progressive systemic sclerosis (PSS), a significant association of HLA antigens A9 and Aw24 (a subgroup of A9) was found with diffuse scleroderma. HLA-Aw23 (a second subgroup of A9) was also increased in the patients, however, this was not statistically significant. Diffuse scleroderma appears to be one of the few diseases that shows an association with the HLA-A locus.

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