Comparative Study
[Antigenic specificity of influenza type A virus hemagglutinin by the method of radioimmunological quantitative analysis]
[Article in
Russian]
- PMID: 78586
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Comparative Study
[Antigenic specificity of influenza type A virus hemagglutinin by the method of radioimmunological quantitative analysis]
[Article in
Russian]
Vopr Virusol.
1978 Mar-Apr.
Abstract
The use of a test system o fa highly purified, antigenically homogeneus hemagglutinin of influenza A/MRC-11 virus and monospecific antiserum permitted to evaluate the potentials of competitive radioimmunoassay in model experiments investigating the antigenic characteristics and content of influenza A (H3N2) virus hemagglutinin. The method proved to be sufficiently specific to differentiate influenza virus strains by antigenic determinants of hemagglutinin, as well as highly sensitive, detecting very small (down to 1 ng) amounts of H3 hemagglutinin in a sample.
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