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Comparative Study
. 1995 Feb;177(4):981-6.
doi: 10.1128/jb.177.4.981-986.1995.

The ars operon of Escherichia coli confers arsenical and antimonial resistance

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Comparative Study

The ars operon of Escherichia coli confers arsenical and antimonial resistance

A Carlin et al. J Bacteriol. 1995 Feb.

Abstract

The chromosomally encoded arsenical resistance (ars) operon subcloned into a multicopy plasmid was found to confer a moderate level of resistance to arsenite and antimonite in Escherichia coli. When the operon was deleted from the chromosome, the cells exhibited hypersensitivity to arsenite, antimonite, and arsenate. Expression of the ars genes was inducible by arsenite. By Southern hybridization, the operon was found in all strains of E. coli examined but not in Salmonella typhimurium, Pseudomonas aeruginosa, or Bacillus subtilis.

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