Case Reports
doi: 10.1007/BF00180544.
Indomethacin treatment in amphotericin B induced nephrogenic diabetes insipidus
Affiliations
- PMID: 7865979
- DOI: 10.1007/BF00180544
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Case Reports
Indomethacin treatment in amphotericin B induced nephrogenic diabetes insipidus
Clin Investig.
1994 Oct.
Abstract
Nephrogenic diabetes insipidus (NDI) is a serious side effect of various drugs. Elevated renal prostaglandin E2 levels have been found in patients with lithium-induced NDI and have been implicated in the pathogenesis. We report the case of a patient who developed NDI following treatment with amphotericin B. Prostaglandin levels were elevated. Indomethacin had an antidiuretic effect and normalized prostaglandin levels.
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