Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Feb;114(1):161-8.
doi: 10.1017/s0950268800052018.

DNA typing of epidemiologically-related isolates of Aspergillus fumigatus

M Birch  1 , N Nolard, G S Shankland, D W Denning
Affiliations

DNA typing of epidemiologically-related isolates of Aspergillus fumigatus

M Birch et al. Epidemiol Infect. 1995 Feb.

Abstract

Invasive aspergillosis is often nosocomially acquired and carries a high mortality. Molecular typing methods to discriminate isolates have now been developed. Using simple restriction endonuclease (Sal1 and Xho1) digestion of total genomic DNA, we have typed 25 epidemiologically-related isolates of A. fumigatus from six hospital episodes of invasive aspergillosis. Eight DNA types were found and in each case the DNA type matched precisely the epidemiological data. Thus DNA typing of A. fumigatus can provide the means to match isolates from linked sources and distinguish isolates from diverse origins.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Crit Rev Clin Lab Sci. 1981;13(1):21-83 - PubMed
    1. Nucleic Acids Res. 1990 Nov 25;18(22):6531-5 - PubMed
    1. N Engl J Med. 1991 Mar 7;324(10):654-62 - PubMed
    1. J Med Vet Mycol. 1991;29(5):339-42 - PubMed
    1. J Clin Pathol. 1992 Apr;45(4):324-7 - PubMed

Publication types

MeSH terms

LinkOut - more resources