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. 1995 Feb 23;1243(2):287-9.
doi: 10.1016/0304-4165(94)00187-3.

Isoelectric restriction of human immunoglobulin isotypes

C Prin  1 , M C Bene, B Gobert, P Montagne, G C Faure
Affiliations

Isoelectric restriction of human immunoglobulin isotypes

C Prin et al. Biochim Biophys Acta. .

Abstract

The partition of human serum immunoglobulins along a pH gradient of ampholynes was investigated using the recently developed method of preparative isoelectrofocusing. Each isotype was demonstrated to display a specific pI range, with limited overlapping. IgA appear to be the most acidic serum immunoglobulins while IgG are clearly basic.

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