The immediate 5'-flanking region of the rat phenylalanine hydroxylase-encoding gene
- PMID: 7875607
- DOI: 10.1016/0378-1119(94)00802-y
The immediate 5'-flanking region of the rat phenylalanine hydroxylase-encoding gene
Abstract
We have characterized the immediate (465 bp) 5'-flanking region of the rat phenylalanine hydroxylase (PAH)-encoding gene. This sequence shows considerable similarity to the 5'-flanking region of the human PAH gene [Konecki et al., Biochemistry 31 (1992) 8363-8368]. Both sequences lack obvious TATA elements; however, putative regulatory sites, including a potential cyclic AMP-response element and glucocorticoid response elements, are present.
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