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. 1994;22(4):273-8.
doi: 10.1515/jpme.1994.22.4.273.

Mast cells in the placenta. Is there a relation to the development of atopic disease in infants before 18 months of age?

A L Mikkelsen  1 , C Felding, L G Larsen, B Andersen, P Sander
Affiliations

Mast cells in the placenta. Is there a relation to the development of atopic disease in infants before 18 months of age?

A L Mikkelsen et al. J Perinat Med. 1994.

Abstract

Objective: To disclose a relation between the amount of mast cells in placenta and the development of atopic disease in children before 18 months of age.

Design: A prospective, descriptive study.

Setting: Two obstetric departments at university hospitals.

Subjects: 67 pairs of mothers and their newborn infants.

Main outcome measures: Family history of atopic disease was taken. The amount of mast cells in placenta was counted. Follow-up questionnaires of the children were evaluated after 18 months.

Results: The follow-up rate was 84%. The number of mast cells in placenta did not differ between atopic and non-atopic children.

Conclusion: A new predictor, the amount of mast cells in placenta was evaluated. In this study the amount of mast cells, in placenta was not predictive of the development of atopic disease before 18 months of age.

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