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Review
. 1995 Mar 9;374(6518):131-4.
doi: 10.1038/374131a0.

Principles of CDK regulation

D O Morgan  1
Affiliations
Review

Principles of CDK regulation

D O Morgan. Nature. .

Abstract

As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.

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