[Phospholipid metabolism in transformed lymphocytes. Molecular mechanism of activation]
- PMID: 787811
- DOI: 10.1007/BF00607931
[Phospholipid metabolism in transformed lymphocytes. Molecular mechanism of activation]
Abstract
An early consequence of lymphocyte stimulation by mitogens is the increased turnover of phospholipid fatty acid moieties. The enzymes catalyzing the selective transfer of fatty acids exhibit a high affinity for highly unsaturated fatty acids. The activation of these acyltransferases leads to a higher content of polyenoic fatty acids and consequently to an increased membrane fluidity.
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