Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1995 Jan;20(1):18-22.
doi: 10.1016/s0968-0004(00)88944-6.

Regulation of Ras-mediated signalling: more than one way to skin a cat

B M Burgering  1 , J L Bos
Affiliations
Review

Regulation of Ras-mediated signalling: more than one way to skin a cat

B M Burgering et al. Trends Biochem Sci. 1995 Jan.

Abstract

A powerful combination of genetics and biochemistry has provided details of how Ras-directed signalling interacts with and is regulated by other cellular signalling pathways. This might ultimately lead to the control of deregulated signalling by oncogenic Ras. Recently, progress has been made in understanding the regulation of Ras-mediated activation of the Raf-1-ERK2 kinase cascade through crosstalk with protein kinase C and cyclic-AMP-dependent protein kinase.

PubMed Disclaimer

MeSH terms

Substances

LinkOut - more resources