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Review
. 1995 Jan;16(1):34-8.
doi: 10.1016/0167-5699(95)80068-9.

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

R S Liblau  1 , S M Singer, H O McDevitt
Affiliations
Review

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

R S Liblau et al. Immunol Today. 1995 Jan.

Abstract

CD4+ T cells play a key role in regulating immune system function. When these regulatory processes go awry, organ-specific autoimmune diseases may develop. Here, Roland Liblau, Steven Singer and Hugh McDevitt explore the thesis that a particular subset of CD4+ T cells, namely T helper 1 (Th1) cells, contributes to the pathogenesis of organ-specific autoimmune diseases, while another subset, Th2 cells, prevents them.

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