[Value of controlled hyperstimulation in intrauterine inseminations]

Abstract

85 patients, with various forms of infertility but who have at least one patent tube, were treated by superovulation with intra uterine insemination of sperm migrated on a discontinuous Percoll gradient. 231 cycles were carried out. 43 clinical pregnancies were achieved. 26 pregnancies were delivered. The mean cycle fecondity rate was 19% (43/231), 18% in the group of male infertility (13/72), 15% in the group of unexplained infertility (13/88), and 23% in the group of various subfertility factors (17/71). There was 20% of twins nor triplets neither quadruplets. There was no sever hyperstimulation. The role of superovulation, the interest of the technic in male infertility, the risk of hyperstimulation and multiple pregnancies are discussed in the text.