Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1976 Oct 23;2(6042):969-70.
doi: 10.1136/bmj.2.6042.969.

Graded compression for preventing deep venous thrombosis

Clinical Trial

Graded compression for preventing deep venous thrombosis

C P Holford. Br Med J. .

Abstract

The physiological effects of static compression of the leg have recently been reinvestigated. Graded compression extending from the ankle to the upper thigh produces the maximum increase in velocity of femoral vein blood flow and the maximum decrease in clearance times of contrast media and radioisotopes from the deep veins of the calf. This type of compression may be easily produced by a specially designed elastic stocking. Graded compression was used in a controlled clinical trial of 98 patients undergoing major operations to assess its effect on isotopically diagnosed deep vein thrombosis. The incidence of deep vein thrombosis was 49% in the control group and 23% in the treated groups. No complications were caused by the stockings. Carefully designed and correctly applied static compression is a safe and effective method of reducing the incidence of deep vein thrombosis.

PubMed Disclaimer

References

    1. N Engl J Med. 1952 May 6;246(10):360-4 - PubMed
    1. Lancet. 1970 Mar 14;1(7646):540-2 - PubMed
    1. Br J Surg. 1974 Mar;61(3):219-23 - PubMed
    1. Arch Surg. 1970 Aug;101(2):149-54 - PubMed
    1. Arch Surg. 1975 Feb;110(2):171-5 - PubMed

Publication types

LinkOut - more resources