Is trisomy 4 a secondary chromosomal abnormality in acute myeloblastic leukemia?
- PMID: 7889518
- DOI: 10.1016/0165-4608(94)00126-v
Is trisomy 4 a secondary chromosomal abnormality in acute myeloblastic leukemia?
Abstract
Cytogenetic studies were carried out in a patient with acute monocytic leukemia (AML-M5) at diagnosis and in relapse. While no chromosome abnormality was detected initially, isolated trisomy 4 was found in relapse. The primary or secondary nature of trisomy 4 as the sole abnormality in AML is discussed.
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