Comparative studies of cefprozil in the management of skin and soft-tissue infections
- PMID: 7889961
- DOI: 10.1007/BF02111354
Comparative studies of cefprozil in the management of skin and soft-tissue infections
Abstract
Six multicenter clinical trials comparing cefprozil with cefaclor, amoxicillin-clavulanate or erythromycin in the management of skin and soft-tissue infections caused by susceptible bacteria demonstrate that cefprozil, given once or twice daily, is an effective chemotherapeutic agent in this context. Its pharmacokinetic behavior is compatible with once-daily or twice-daily administration, with a probability of improved patient compliance. Safety and tolerability compare favorably with other agents used in skin and soft-tissue infections.
Similar articles
-
Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media.Eur J Clin Microbiol Infect Dis. 1994 Oct;13(10):857-65. doi: 10.1007/BF02111353. Eur J Clin Microbiol Infect Dis. 1994. PMID: 7889960 Review.
-
Efficacy and safety of cefprozil versus other beta-lactam antibiotics in the treatment of lower respiratory tract infections.Eur J Clin Microbiol Infect Dis. 1994 Oct;13(10):851-6. doi: 10.1007/BF02111352. Eur J Clin Microbiol Infect Dis. 1994. PMID: 7889959 Review.
-
Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential.Drugs. 1993 Feb;45(2):295-317. doi: 10.2165/00003495-199345020-00008. Drugs. 1993. PMID: 7681376 Review.
-
Comparative efficacy and safety of oral fleroxacin and amoxicillin/clavulanate potassium in skin and soft tissue infections.Am J Med. 1993 Mar 22;94(3A):159S-165S. Am J Med. 1993. PMID: 8452174 Clinical Trial.
-
Comparison of cefprozil with other antibiotic regimens in the treatment of children with acute otitis media.Clin Infect Dis. 1992 Jun;14 Suppl 2:S204-8; discussion S209-11. doi: 10.1093/clinids/14.supplement_2.s204. Clin Infect Dis. 1992. PMID: 1617039 Review.
Cited by
-
Once-daily oral gatifloxacin versus oral levofloxacin in treatment of uncomplicated skin and soft tissue infections: double-blind, multicenter, randomized study.Antimicrob Agents Chemother. 2001 Aug;45(8):2358-62. doi: 10.1128/AAC.45.8.2358-2362.2001. Antimicrob Agents Chemother. 2001. PMID: 11451697 Free PMC article. Clinical Trial.
-
Staphylococcal skin infections in children: rational drug therapy recommendations.Paediatr Drugs. 2005;7(2):77-102. doi: 10.2165/00148581-200507020-00002. Paediatr Drugs. 2005. PMID: 15871629 Review.
-
Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections.Indian J Pharmacol. 2015 Jul-Aug;47(4):365-9. doi: 10.4103/0253-7613.161254. Indian J Pharmacol. 2015. PMID: 26288467 Free PMC article. Clinical Trial.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical