Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1994;76(8):761-9.
doi: 10.1016/0300-9084(94)90080-9.

Regulation of heme-regulated eIF-2 alpha kinase and its expression in erythroid cells

J J Chen  1 , J S Crosby, I M London
Affiliations
Review

Regulation of heme-regulated eIF-2 alpha kinase and its expression in erythroid cells

J J Chen et al. Biochimie. 1994.

Abstract

In this article we focus first on the molecular mechanisms controlling the activity of the heme-regulated translational inhibitor, HRI, in erythroid cells. Then we discuss the tissue-specific expression of HRI. The experimental evidence obtained to date indicates that the major physiological role of HRI is in adjusting the synthesis of globin to the availability of heme.

PubMed Disclaimer

Publication types

LinkOut - more resources