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. 1994 Nov 1;24(1):27-33.
doi: 10.1006/geno.1994.1578.

A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1)

B Kraus  1 , M Pohlschmidt, A L Leung, G G Germino, A Snarey, M C Schneider, S T Reeders, A M Frischauf
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Free article

A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1)

B Kraus et al. Genomics. .
Free article

Abstract

The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, we isolated a new member of the cyclin family. We have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown.

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