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Case Reports
. 1994 Aug-Sep;96(8-9):290-2.

[VNTR-PCR in diagnosis of inherited Rb gene mutation]

[Article in Polish]
S Zajaczek  1 , B Górski, T Débniak, J Podolski, J Lubiński, Z Krzystolik, T Iwanicka, Z Sagan
Affiliations
  • PMID: 7897998
Case Reports

[VNTR-PCR in diagnosis of inherited Rb gene mutation]

[Article in Polish]
S Zajaczek et al. Klin Oczna. 1994 Aug-Sep.

Abstract

Molecular genetic analysis of DNA by PCR-VNTR was performed in a family with hereditary retinoblastoma presenting some difficulties in pedigree analysis. PCR-VNTR allowed to perform a more accurate counselling in this family. Analysis of the way of transmission, carrier status exclusion (in two persons) and confirmation (in one) was possible only by VNTR-PCR.

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