Identification of a common antigen of herpes simplex virus bovine herpes mammillitis virus, and B virus
- PMID: 78988
- PMCID: PMC525895
- DOI: 10.1128/JVI.26.3.712-717.1978
Identification of a common antigen of herpes simplex virus bovine herpes mammillitis virus, and B virus
Abstract
In immunoelectrophoretic analyses one common antigen was demonstrated in antigen preparations from herpes simplex virus types 1- and 2- (HSV-1 and HSV-2), bovine herpes mammillitis (BHM) virus-, and B virus-infected cells solubilized by Triton X-100. The antigen was also demonstrated in solubilized purified HSV-1 and BHM virus. The common antigen was identified as antigen 11 of HSV-1 or HSV-2. Differences were found in the polypeptide composition of the related antigens when isolated from the four different herpesviruses, but a glycopolypeptide with a molecular weight of 125,000 was present in each of the four different antigen preparations, indicating that this polypeptide carried the common antigenic determinants.
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