[Experimental testing of Dexon, Vicryl and Gore-Tex mesh used to complete the abdominal wall]

Abstract

Injuries of abdominal integuments, operations and reoperations of hernias, injuries of a spleen, defects in the wall of the chest and diaphragm cause that the need for substitute materials and alloplastic materials for completing those defects is large. To satisfy this tests have been made experiments with absorbable--Dexon, made by Davis and Geck enterprise, Ethicon and non-absorbable--Teflon made by Gore-Tex enterprise according to the proposition of H. Kuś. The experimental tests were made on 30 rabbits of the white New Zealand breed which weighted 2-3 kg. On the hypogastrium in the distance of 3 cm from the white line on its both sides defects of the size 2 x 3 cm were made. On the right side both fascial-muscular layers of the external and internal oblique muscle of abdomen were cut out but the peritoneum was left while on the left side only one layer was cut out. The defects were completed with nets and fixed with interrupted sutures and then with continuous suture. During the operation the behaviour of the nets in the operation area and the difficulties in connecting the nets with the animals' tissues were tested. Sections of the animals and macroscopic tests were made 7, 14, 21 and 90 days after the implantation of each surgical net estimating the process of healing and resorption of the absorbable nets. The state of the organs of the abdominal cavity was also estimated. Microscopic tests consisted of estimation of the histological specimens made from the tissues taken during the sections of the animals. At the estimation of the surgical convenience of the tested nets it turned out that each of them is very convenient. The differences were in the fact that the Dexon and Vicryl nets had little elasticity and extensibility and after cutting there was a little shredding of their edges. The Gore-Tex net, on the other hand, due to its specific spongy structure, had little extensibility, good elasticity and a complete lack of shredding of the edges after cutting. The macroscopic tests carried out in the planned terms did not showed any deformation or handicap of the functions of the abdominal integuments. The nets implantation did not cause displacement of the internal organs nor intraperitoneal adhesions. On the basis of the microscopic investigation it was noticed that the absorbable surgical nets underwent progressing resorption in the tissues in the period of 21 to 90 days after the implantation.(ABSTRACT TRUNCATED AT 400 WORDS)