Abstract

PIP: In order to determine the effectiveness of the preparation Quinestrol, a 3-cyclo-pentyl ether of ethinyl estradiol, in inhibiting the level of postpartum lactation, 60 patients received 4 mg of Quinestrol within 6 hours of delivery, and 60 others a placebo of lactose at the same time. The patients were observed for a period of 4 days. Absence of pain, lactation, and engorgement were the criteria for success. Lactation was successfully inhibited in 46 of the 60 using Quinestrol (76.6%). 8 patients were considered failures. Only 6 of those patients administered the lactose placebo had lactation successfully suppressed. Literature from other sources on this topic is discussed.