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. 1978 Jul 29;2(8083):239-41.
doi: 10.1016/s0140-6736(78)91748-8.

Does bile promote extra-colonic cancer?

Does bile promote extra-colonic cancer?

A B Lowenfels. Lancet. .

Abstract

The incidence of biliary-tract cancer and of several other gastrointestinal tumours is increased when conditions favour conversion of bile acids to more active substances. This may indicate that bacterial degradation of bile salts is related to the pathogenesis of cancer in parts of the alimentary tract other than the large bowel.

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