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. 1976 Oct;73(10):3651-5.
doi: 10.1073/pnas.73.10.3651.

A mutant of Saccharomyces cerevisiae defective for nuclear fusion

J Conde, G R Fink

A mutant of Saccharomyces cerevisiae defective for nuclear fusion

J Conde et al. Proc Natl Acad Sci U S A. 1976 Oct.

Abstract

A mutant unable to fuse nuclei during mating has been isolated from standard wild-type Saccharomyces cerevisiae. Tetrad analysis of the mutation responsible for this defect (kar1-1) shows that it segregates as a single Mendelian factor. The defect kn kaf1-1 appears to be nuclear limited. Cytological and genetic evidence shows that in this mutant the events associated with zygote formation are normal until the point of nuclear fusion. The consequence of this defect is the formation of a multinucleate zygote which in subsequent divisions can segregate heterokaryons and haploid heterplasmons.

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References

    1. Proc Natl Acad Sci U S A. 1957 Oct 15;43(10):919-23 - PubMed
    1. Mol Gen Genet. 1975;136(4):327-35 - PubMed
    1. J Bacteriol. 1976 Jun;126(3):1339-41 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Jun;66(2):352-9 - PubMed
    1. Exp Cell Res. 1973 Jan;76(1):111-7 - PubMed

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